Gastrointestinal Symptoms and IgG Food Allergies

Type III food allergies may play a role in chronic ailments like Irritable Bowel Syndrome or Crohn’s disease

Stomachache, bloating, diarrhoea and constipation are common gastrointestinal disorders. Many people suffer from such chronic complaints of unclear origin, often accompanied by tiredness and exhaustion. Food hypersensitivities may be triggers of these ailments, among them IgG food allergies (type III). Two common gastrointestinal disorders are Irritable Bowel Syndrome (IBS) and Crohn’s disease (CD).

Can IgG antibodies against trigger foods play a role in IBS with diarrhea? Can a dietary elimination based on the presence of IgG antibodies to food positively influence the patient ́s symptoms and course of disease?


77 patients with IBS symptoms including diarrhea were compared with a group of 26 patients without IBS. In the IBS group was a significantly higher proportion of patients with elevated IgG antibodies, compared to the group of non-IBS patients. A 12 week diet without foods with an elevated IgG level against these potential trigger foods was conducted for 35 IBS patients.


The elimination diet based on foodstuffs to which the patient had developed increased quantities of IgG antibodies led to a significant reduction in all irritable bowel symptoms compared with the baseline scores.


The study showed that IgG antibodies against food play a role in IBS. For IBS patients with diarrhea, an IgG antibody test combined with an elimination diet can positively influence the symptoms and patient ́s well-being.

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